Teoreler:PBPK-Mouse

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Model Parameters

Preloaded drug profile:

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Log P:

Property:

pKa1, pKa2 (if any):

Protein binding (%):

Blood-to-plasma ratio:

Route of administration:

In vitro absorption type:

Absorption value:

x 10^-6

Release rate (h⁻¹):Infusion time (h):

Polar surface area (Å²):

Hydrogen bond donors:

Clearance type:

Clearance value:

F value:

Enzyme 1:

Enzyme 1 value:

Enzyme 2:

Enzyme 2 value:

Enzyme 3:

Enzyme 3 value:

fu_gut:

fu_liv:

V_d method:

Renal clearance:

Sex:

FemaleMaleBoth

Dose:

Dosing interval:

Dose repeats:

Dose end time:

Simulation time:

Time units:

Population:

Target concentration:

Concentration units:

Animal strain:

Animal age (in weeks):

Absorption scalar:

Clearance scalar:

Distribution scalar:

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Time units:

Concentration units: